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  大学ホームページ 図書館ホームページ 運営規程 登録・公開許諾書 パンフレット  更新日：2024/05/22    件数：7,050件     TOP  Language   JapaneseEnglishヘルプ No.1(全1件)     検索画面戻る一覧 Sugar-responsive smart materials based on phenylboronic acid and cyclodextrinこのページを印刷URL:   ダウンロード  IDJOS-s10847-019-00899-6著者：名前江川, 祐哉/関, 智宏/三木, 涼太郎/関, 俊暢著者：別形式Egawa, Yuya / Seki, Tomohiro / Miki, Ryotaro / Seki, Toshinobu著者：カナエガワ, ユウヤ/セキ, トモヒロ/ミキ, リョウタロウ/セキ, トシノブ著者：所属城西大学薬学部 / 城西大学薬学部 / 城西大学薬学部 / 城西大学薬学部著者：所属(別形式）Josai University, Faculty of Pharmacy and Pharmaceutical Sciences / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences著者版フラグauthor出版者Springer冊子ISSN13883127電子ISSN15731111掲載誌名Journal of Inclusion Phenomena and Macrocyclic Chemistry巻94刊行年月2019-06開始ページ1終了ページ10コンテンツ作成日2018-12-11コンテンツ修正日2019-03-15コンテンツ登録日2020-07-21識別番号：DOIinfo:doi/10.1007/s10847-019-00899-6識別番号：DOI（リンク）https://doi.org/10.1007/s10847-019-00899-6抄録This review focuses on sugar-responsive materials based on phenylboronic acid (PBA) as a sugar-sensing motif and cyclodextrins (CyDs) as a basic skeleton of smart materials. PBA modified α-CyD (PBA-α-CyD) forms a supramolecular polymer through intermolecular interactions between PBA part and CyD cavity. Similarly, PBA-β-CyD forms a head-to-head dimer. Meanwhile, combining PBA-γ-CyD and polyethylene glycol (PEG) produces a molecular necklace. Additionally, combining PBA-modified PEG and native α-CyD or γ-CyD results in another type of molecular necklace. These supramolecular structures are obtained as powders, and their solubility increases in the presence of sugar. Besides the powder type, a unique gel is formed through crosslinking polyvinyl alcohol with PBA-triazole-γ-CyD (PBA-Tri-γ-CyD). This gel can contain model drug, and it shows sugar-responsive drug release. The sugar response of all of these smart materials can be explained by the concept of equilibrium. The smart materials are constructed with CyD-guest interactions. The CyD-guest equilibrium moves by a reaction between sugar and PBA moiety attached to the smart material. In these smart materials, sugar induces a dissociation in the CyD-guest interaction, and this dissociation results in sugar-induced disintegration of CyD-guest supramolecular structures.キーワードCyclodextrin/Gel/Phenylboronic acid/Pseudopolyrotaxane/Smart material/Sugar response/Supramolecular polymer注記This is a post-peer-review, pre-copyedit version of an article published in Journal of Inclusion Phenomena and Macrocyclic Chemistry. The final authenticated version is available online at: https://doi.org/10.1007/s10847-019-00899-6言語 eng資源タイプtextジャンル01学術雑誌論文 / Journal Articleフォーマットapplication/pdf権利Copyright © Springer Nature B.V. 2019このアイテムを表示する：本文(pdf)( 754.2KB) ダウンロード回数： 回このアイテムを表示する：URIhttps://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-s10847-019-00899-6URL:G0000284repository_JOS-s10847-019-00899-6  var xurl =document.URL; var xrecid = 'G0000284repository_JOS-s10847-019-00899-6'; var xReg = new RegExp(/(.*meta.*\/)/); var xmatch = xurl.match(xReg); var urlstr = RegExp.$1; if( xmatch) jQuery('a#infolib_permalink').html( urlstr + xrecid ); detailcont["max"] = '0'; detailcont["detailViewFlg"] = '0'; var xswitchViewButton = jQuery('div#detailContentsSwicher'); xswitchViewButton.show(); var xEditorButton = jQuery('div#detailEditor'); if( xEditorButton.length) { xpanel.xEditorPrime = "JOS-s10847-019-00899-6"; xEditorButton.show(); } detailcont["contentsDspMax"] = '5'; detailcont["show"] = 'all'; detailcont["contentsDbId"] = 'G0000284repository'; detailcont["currentContNo"] = '0'; meta.detailSetViewerHeight(); Copyright(C) 2010 Josai University. All Rights Reserved　　※Internet Explorer をお使いの方はVer.8以上をご利用願います。