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Researchers Details of a Researcher Home Japanese このページはJavascriptを使用しています。すべての機能を使用するためにはJavascript を有効にする必要があります。 　 Personnel Information 　 Profile 　 Degree 　 Research Interests 　 From School 　 From Graduate School 　 Employment Record in Research 　 External Career 　 Professional Memberships 　 Qualification Acquired 　 Research Activity 　 Papers Updated on 2024/02/26 AKUTSU Hiroshi Affiliation Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Title Assistant Professor External Link To the head of this page.▲ Degree 【 display / non-display 】 To the head of this page.▲ Degree 【 display / non-display 】 博士（薬学） ( 2020.07   東京薬科大学 ) To the head of this page.▲ Research Interests 【 display / non-display 】 To the head of this page.▲ Research Interests 【 display / non-display 】 有機化学 有機分子触媒 To the head of this page.▲ From School 【 display / non-display 】 To the head of this page.▲ From School 【 display / non-display 】 Tokyo University of Pharmacy and Life Science   Faculty of Pharmaceutical Science   Graduated - 2015.03 　 More details Country：Japan To the head of this page.▲ From Graduate School 【 display / non-display 】 To the head of this page.▲ From Graduate School 【 display / non-display 】 Tokyo University of Pharmacy and Life Science   Graduate School, Division of Pharmaceutical Sciences   Doctor&＃39;s Course   Unfinished Course 2015.04 - 2018.06 　 More details Country：Japan To the head of this page.▲ Employment Record in Research 【 display / non-display 】 To the head of this page.▲ Employment Record in Research 【 display / non-display 】 Josai University   Faculty of Pharmaceutical Sciences   Department of Pharmaceutical Sciences   Assistant Professor 2020.04 To the head of this page.▲ External Career 【 display / non-display 】 To the head of this page.▲ External Career 【 display / non-display 】 Tokyo University of Pharmacy and Life Science   Research Assistant 2018.07 - 2020.03 　 More details Country：Japan To the head of this page.▲ Professional Memberships 【 display / non-display 】 To the head of this page.▲ Professional Memberships 【 display / non-display 】 日本薬学会 2016.02 To the head of this page.▲ Qualification Acquired 【 display / non-display 】 To the head of this page.▲ Qualification Acquired 【 display / non-display 】 Pharmacist Hazardous Material Handler (first kind) To the head of this page.▲   Papers 【 display / non-display 】 To the head of this page.▲ Papers 【 display / non-display 】 Asymmetric Direct Vinylogous Conjugate Addition of α,β-Unsaturated γ-Butyrolactam to Acyl Acrylonitriles using Organocatalysts Reviewed D. Ishii, S. Hirashima, K. Nakashima, Y. Matsushima, T. Sakai, H. Akutsu, T. Miura Asian Journal of Organic Chemistry   e202300082   2023.02 Asymmetric Direct Vinylogous Conjugate Addition of Substituted Furanone Derivatives to ( E )‐ and ( Z) ‐Benzoyl Acrylonitriles Using Organocatalysts Reviewed Daiki Ishii, Shin‐ichi Hirashima, Hiroshi Akutsu, Kosuke Nakashima, Yasuyuki Matsushima, Takaaki Sakai, Tsuyoshi Miura Asian Journal of Organic Chemistry   11 ( 5 )   2022.03 　More details Publishing type：Research paper (scientific journal)   Publisher：Wiley   AbstractDiaminomethylenemalononitrile organocatalysts efficiently promoted the asymmetric direct vinylogous conjugate addition of α‐angelica lactone to (E)‐ and (Z)‐benzoyl acrylonitrile derivatives. The synthesized products bear vicinal tertiary and quaternary stereogenic centers with excellent enantioselectivities (up to 98% ee). This report is the first successful example of the stereoselective conjugate addition using (Z)‐benzoyl acrylonitriles as Michael acceptor. DOI： 10.1002/ajoc.202200048 researchmap Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ajoc.202200048 Diaminomethylenemalononitrile as a Chiral Single Hydrogen Bond Catalyst: Application to Enantioselective Conjugate Addition of α‐Branched Aldehydes Reviewed Masahiro Kawada, Ryo Tsuyusaki, Kosuke Nakashima, Hiroshi Akutsu, Shin‐ichi Hirashima, Takashi Matsumoto, Hikaru Yanai, Tsuyoshi Miura Chemistry – An Asian Journal   16 ( 16 )   2272 - 2275   2021.08 　More details Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley   DOI： 10.1002/asia.202100487 Asymmetric Direct Vinylogous Conjugate Addition of Substituted Furanone Derivatives to Benzoyl Acrylonitrile: Stereoselective Synthesis Toward Bicyclic γ-Lactams Reviewed Daiki Ishii, Shin-ichi Hirashima, Kosuke Nakashima, Hiroshi Akutsu, Takaaki Sakai, Yasuyuki Matsushima, Masahiro Kawada, Tsuyoshi Miura Organic Letters   23 ( 2 )   480 - 485   2021.01 　More details Language：English   Publishing type：Research paper (scientific journal)   Publisher：American Chemical Society (ACS)   DOI： 10.1021/acs.orglett.0c04004 Asymmetric Conjugate Addition of α-Cyanoketones to Benzoyl Acrylonitrile Derivatives Using a Diaminomethylenemalononitrile Organocatalyst Reviewed Hiroshi Akutsu, Kosuke Nakashima, Yuta Kanetsuna, Masahiro Kawada, Shin-ichi Hirashima, Tsuyoshi Miura Synthesis   52 ( 24 )   3874 - 3880   2020.09 　More details Language：English   Publishing type：Research paper (scientific journal)   Publisher：Georg Thieme Verlag KG   DOI： 10.1055/s-0040-1707285 display all >> To the head of this page.▲   Copyright © Josai University, All Rights Reserved.