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  大学ホームページ 図書館ホームページ 運営規程 登録・公開許諾書 パンフレット  更新日：2024/05/22    件数：7,050件     TOP  Language   JapaneseEnglishヘルプ No.1(全1件)     検索画面戻る一覧 Identification and Characteristics of Time-Related Shifts in Suicide-Related Event Frequency During Smoking Cessation Treatment with Vareniclineこのページを印刷URL:   ダウンロード  IDJOS-ijms.19877著者：名前秋元, 勇人/脇山, 春名/大島, 新司/根岸, 彰生/大原, 厚祐/沼尻, 幸彦/冲田, 光良/大嶋, 繁/井上, 直子/小林, 大介著者：別形式Akimoto, Hayato / Wakiyama, Haruna / Oshima, Shinji / Negishi, Akio / Ohara, Kousuke / Numajiri, Sachihiko / Okita, Mitsuyoshi / Ohshima, Shigeru / Inoue, Naoko / Kobayashi, Daisuke著者：カナアキモト, ハヤト/ワキヤマ, ハルナ/オオシマ, シンジ/ネギシ, アキオ/オオハラ, コウスケ/ヌマジリ, サチヒコ/オキタ, ミツヨシ/オオシマ, シゲル/イノウエ, ナオコ/コバヤシ, ダイスケ著者：所属城西大学薬学部 / 城西大学薬学部 / 城西大学薬学部 / 城西大学薬学部 / 城西国際大学薬学部 / 城西大学薬学部 / 城西大学薬局 / 城西大学薬学部 / 城西大学薬学部 / 城西大学薬学部著者：所属(別形式）Josai University, Faculty of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences / Josai International University, Faculty of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences / Josai University Pharmacy / Josai University, Faculty of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences著者版フラグpublisher出版地New South Wales出版者Ivyspring International PublisherNCIDAA12050919電子ISSN14491907掲載誌名International Journal of Medical Sciences巻14号10刊行年月2017開始ページ920終了ページ926コンテンツ作成日2017-03-01コンテンツ修正日2017-05-17コンテンツ登録日2017-10-31識別番号：DOIinfo:doi/10.7150/ijms.19877識別番号：DOI（リンク）http://doi.org/10.7150/ijms.19877抄録Objectives: To survey time-related shifts in number of suicide-related events (SRE) during smoking cessation treatment with varenicline (VAR) in cases from the U.S. Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS), as well as the characteristics of these shifts.Methods: We isolated cases from the FAERS database involving VAR usage where SRE was reported as an adverse event (SRE+/VAR+ case) and established a histogram of SRE+/VAR+ case numbers per week. Furthermore, we focused on “cases reporting specific adverse events prior to drug usage start” using X-bar and R chart concepts. We also attempted to exclude the influence of smoking history from the created histogram. Moreover, we constructed a histogram on central nervous system adverse events, which were frequently seen during VAR usage.Results: By removing the effects of smoking history, SRE onset signals were detected over a long period from the start of VAR use. However, expression signals for nausea and abnormal dreams were detected only in the early VAR administration period.Discussion: These results suggest that VAR use-induced SRE is expressed over a long timeframe from the start of treatment. Additionally, the period of SRE expression signal detection was longer than that of the other central nervous system adverse events (nausea and abnormal dreams). Therefore, SRE onset must be carefully monitored during smoking cessation treatment with VAR over the entire treatment period.キーワードSuicide-Related Event/Varenicline/Case Study/FAERS/Smoking Cessation言語 eng資源タイプtextジャンル01学術雑誌論文 / Journal Articleフォーマットapplication/pdf権利Copyright © 2017 Ivyspring International Publisherこのアイテムを表示する：本文(pdf)( 720.5KB) ダウンロード回数： 回このアイテムを表示する：URIhttp://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-ijms.19877URL:G0000284repository_JOS-ijms.19877  var xurl =document.URL; var xrecid = 'G0000284repository_JOS-ijms.19877'; var xReg = new RegExp(/(.*meta.*\/)/); var xmatch = xurl.match(xReg); var urlstr = RegExp.$1; if( xmatch) jQuery('a#infolib_permalink').html( urlstr + xrecid ); detailcont["max"] = '0'; detailcont["detailViewFlg"] = '0'; var xswitchViewButton = jQuery('div#detailContentsSwicher'); xswitchViewButton.show(); var xEditorButton = jQuery('div#detailEditor'); if( xEditorButton.length) { xpanel.xEditorPrime = "JOS-ijms.19877"; xEditorButton.show(); } detailcont["contentsDspMax"] = '5'; detailcont["show"] = 'all'; detailcont["contentsDbId"] = 'G0000284repository'; detailcont["currentContNo"] = '0'; meta.detailSetViewerHeight(); Copyright(C) 2010 Josai University. All Rights Reserved　　※Internet Explorer をお使いの方はVer.8以上をご利用願います。