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--> Frontier Research Institute for Interdisciplinary SciencesTohoku University Directions 日本語 English CONTACT 日本語 English About FRISGreetingsOverviewMissionsOrganizationTenure track system in FRISMaps & DirectionsPublicationAnnual MeetingAbstract for Annual MeetingConsultation DeskResearcherAdvanced Interdisciplinary Research DivisionHiroshi MasumotoTakehito ShimatsuTakashi ItohKenji TomaShinsuke NiwaTakaaki TomaiCreative Interdisciplinary Research DivisionYuanyuan GuoMasaki OkumuraNguyen Tuan HungHiroshi UenoToshiharu IchinoseYuta KudoHiroya AbeYuta NakayasuNaoya KitajimaDaniel Pastor-GalanYasunori OkamotoTakuro IshiiMasaki YamadaYuta YamaneKexin XiongKohei ShimokawaShinichi SatoKotaro YasuiSUN SaiYuji SaitoAtsushi TaharaKyoko ChibaYuka HatanoHakuto SuzukiKaoru HiramotoHideaki T. MatsubayashiAseel Mahmoud Suleiman MarahlehSakura KiuchiShigeo S. 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Trains transport people, trucks carry packages for convenience stores, tankers transport oil... These systems combine intricately to sustain modern life. Similarly, there is a mechanism within our bodies that transports cargo. My research focuses on this transport system - intracellular transport. My focus is on motor proteins, which function as vehicles within cells. Motor proteins are typically in a brake-locked state (inactive form) to prevent energy waste. However, when cargo is loaded, the brake is released, activating them to start moving. The mechanism underlying this process is still not well understood. I am using a technique called single-molecule observation, which allows the observation of the movement of individual protein molecules, to investigate the mechanism by which motor proteins are activated. Mutations in motor protein genes are related to various human diseases. By elucidating how motor proteins are activated, I hope to contribute to understanding the pathogenesis of these diseases and establishing therapeutic approaches. 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