いざわせいか
<ウェブサイト名>
<現在の時刻>
Researchers Details of a Researcher Home Japanese このページはJavascriptを使用しています。すべての機能を使用するためにはJavascript を有効にする必要があります。 Personnel Information Profile Research Interests Employment Record in Research Research Activity Papers Misc Presentations Contribution to Society Committee Memberships Updated on 2024/04/10 YAMANOI Takashi Affiliation Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Title Professor External Link To the head of this page.▲ Research Interests 【 display / non-display 】 To the head of this page.▲ Research Interests 【 display / non-display 】 糖質科学 有機合成化学 分子認識 To the head of this page.▲ Employment Record in Research 【 display / non-display 】 To the head of this page.▲ Employment Record in Research 【 display / non-display 】 Josai University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Professor 2014.04 To the head of this page.▲ Papers 【 display / non-display 】 To the head of this page.▲ Papers 【 display / non-display 】 A Synthetic Approach for Hepta-Branched β-Cyclodextrins Bearing Heterogeneous Carbohydrate Residues at Their Primary Side via a One-Pot Process with a Simultaneous Click Chemistry Reaction Reviewed Yoshiki Oda, Takashi Yamanoi Synlett eFirst 2024.01 More details Language：English Publishing type：Research paper (scientific journal) Preparation of Fluorous Aza-crown Ether with Two Bisfluorous Chain Type Propionyl Groups: An Investigation of its Partition Ratios in Fluorous Biphasic Systems and Recyclability During SN2-type Acetoxylation Reactions Reviewed Takashi Yamanoi, Kenji Koike and Yoshiki Oda Letters in Organic Chemistry 24 ( 1 ) 12 - 15 2024.01 More details Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) β-Cyclodextrins bearing ethylene glycol chains at their primary side: their preparations and evaluation as solubilizing agents for 17-β-estradiol and nuclear magnetic resonance structural analysis of a 17-β-estradiol inclusion complex Reviewed Yoshiki Oda, Junki Nakagawa, Kaname Kasturaya, and Takashi Yamanoi Journal Inclusion Phenomena & Macrocyclic Chemistry 103 421 - 428 2023.12 More details Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) SYNTHESIS OF HEPTA-ARBUTIN-BRANCHED β-CYCLODEXTRINS AT THEIR PRIMARY SIDES VIA CLICK REACTION Reviewed Yoshiki Oda, Junki Nakagawa, and Takashi Yamanoi HETEROCYCLES 106 ( 12 ) 1971 - 1976 2023.12 More details Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) SYNTHESES OF TWO NEW FLUOROUS CROWN ETHERS CARRYING SUGAR MOLECULES WITH A MULTIVALENT BFP MODIFICATION: INVESTIGATIONS OF THEIR PARTITION RATIOS IN FLUOROUS BIPHASIC SYSTEMS AND RECYCLABILITY DURING ACETOXYLATION REACTION Reviewed Takashi Yamanoi, Kenji Koike, Taro Koda, and Yoshiki Oda, HETEROCYCLES 106 ( 5 ) 841 - 846 2023.05 More details Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) display all >> To the head of this page.▲ Misc 【 display / non-display 】 To the head of this page.▲ Misc 【 display / non-display 】 Stereoselectivity of D-psicofuranosylation reactions catalyzed by scandium triflate Reviewed T. Yamanoi, T. Ishiyama, and M. Watanabe Proceedings of the Fifth Symposium of International Society of Rare Sugars 29 - 33 2011 More details Authorship：Lead author Language：English Publishing type：Article, review, commentary, editorial, etc. (international conference proceedings) Reactions and uses of artificial ketoses Invited Reviewed T. Yamanoi and S. Matsuda Heterocycles 79 163 - 194 2009 More details Authorship：Lead author Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal) H and 13C DOSY spectra of the mixed sample of α-cyclodextrin and phenyl alpha-D-(13C6)glucopyranoside Reviewed Y. Oda, S. Matsuda, T. Yamanoi, A. Murota, and K. Katsuraya Proceeding of the 14th International Symposium on Cyclodextrins 417 - 420 2008 More details Authorship：Lead author Language：English Publishing type：Article, review, commentary, editorial, etc. (international conference proceedings) Synthetic approach from D-mannose to 2,7-anhydro-D-sedoheptulose Reviewed S. Matsuda and T. Yamanoi Proceedings of the Fourth Symposium of International Society of Rare Sugars 84 - 88 2008 More details Language：English Publishing type：Article, review, commentary, editorial, etc. (international conference proceedings) Glycosidation of the rare sugars, L-fructose and D-psicose Reviewed T. Ishiyama, T. Yamanoi, and M. Watanabe Proceedings of the Fourth Symposium of International Society of Rare Sugars 76 - 80 2008 More details Language：English Publishing type：Article, review, commentary, editorial, etc. (international conference proceedings) display all >> To the head of this page.▲ Presentations 【 display / non-display 】 To the head of this page.▲ Presentations 【 display / non-display 】 シクロデキストリンによるドキソルビシン会合構造体のＮＭＲ解析 鬘谷 要, 小田慶喜, 山ノ井孝 第35回シクロデキストリンシンポジウム 日本シクロデキストリン学会 More details Event date： 2018.09 Language：Japanese Presentation type：Poster presentation Venue：甲府 糖鎖抗原を用いた迅速な多包虫症診断法の開発 小泉 晶彦、安保 秀美、山ノ井 孝 第37回糖質学会 More details Event date： 2018.08 Language：Japanese Presentation type：Poster presentation Synthesis of β-cyclodextrin derivatives multivalently conjugated with carbohydrate moieties through click chemistry reaction International conference Y. Oda, J. Nakagawa, M. Watanabe, T. Yamanoi The 19th International Cyclodextrin Symposium More details Event date： 2018.04 Language：English Presentation type：Poster presentation Venue：東京 The cyclodextrins (CyDs) play a functional role as scaffold molecules for enabling to conjugate organic compounds to CyDs via co-valent bonds. The structural feature of CyDs usefully leads to the development of CyD-based functional materials. In CyD chemistry, it is currently one of the most significant subjects to develop the scaffold use of CyD molecules. The CyD derivatives with multivalent carbohydrate ligands are expected to be drug carriers. Therefore, this study describes the design and synthesis of newly several β-CyD derivatives multivalently conjugated with carbohydrate moieties through click chemistry reaction. Scheme 1 presents the synthetic approch for the β-CyD derivative 3 conjugated with seven glucopyranose moieties from β-CyD and β-arbutin (natural product, p-hydroxyphenyl β-D-glucopyranoside). The azide-alkyne Huisgen cycloaddition between the acetylated β-arbutin derivative 1 with a propargyl group and the acetylated hepta(6-azido-6-deoxy)-β-CyD derivative 2 using CuSO4 and sodium ascorbate in THF / H2O (1 / 1) was smoothly promoted by microwave irradation to afforded the precursor, acetyl protected β-CyD derivative. The following deacetylation of 3 gave the desired β-CyD derivative 3 in good yield.Several types of β-CyD derivatives with seven carbohydrate moieties from α-arbutin (p-hydroxyphenyl α-D-glucopyranoside), mannopyranose (Man) or 2-acetoamido-2-deoxy-glucopyranose (GlcNAc), were also sucessfully demonstrated. Furthermore, we investigated the synthesis of hybride types of β-CyD derivatives multivalently with mixed carbohydrates moieties (β-arbutin, α-arbutin, Man, and GlcNAc). インフルエンザウイルス捕獲機能を有する糖鎖多分岐シクロデキストリン誘導体の合成研究 International conference 山ノ井孝、小田慶喜、苫米地祐輔、中川純樹、渡邊幹夫、山本憲二 第34回シクロデキストリンシンポジウム シクロデキストリン学会 More details Event date： 2017.08 - 2017.09 Language：Japanese Presentation type：Oral presentation (general) Venue：名古屋 Endo-M酵素を用いたグルコース七残基分岐β-CyDへのN-結合型糖 鎖の集積化 苫米地 祐輔, 中川 純樹, 渡邊 幹夫, 小田 慶喜, 山本 憲二, 山ノ 井 孝 第36回日本糖質学会年会 日本糖質学会 More details Event date： 2017.07 Language：Japanese Presentation type：Poster presentation Venue：旭川 display all >> To the head of this page.▲ Committee Memberships 【 display / non-display 】 To the head of this page.▲ Committee Memberships 【 display / non-display 】 東京糖鎖研究会 幹事会員 2016.04 More details Committee type：Academic society 日本糖質学会 評議員 2003.07 More details Committee type：Academic society シクロデキストリン学会 評議員 2003.04 More details Committee type：Academic society To the head of this page.▲ Copyright © Josai University, All Rights Reserved.
